One of the main criticisms of bioidentical hormone therapy is that “there are no studies on bioidentical hormones.” In fact, there are many excellent publications that demonstrate the benefits of bioidentical hormone therapy. Some of the studies show a greater margin of safety with bioidentical progesterone over the non-bioidentical progestin, Provera. Those that support Premarin and Provera point to a number of studies that were done. However, 26 of them were biased and, what’s worse, the bias was covered up. If Wyeth needed to “give credit” to other physicians for their research on their own products, what were they trying to cover up? What did they know that they weren’t saying? Why weren’t there independent groups that could have demonstrated the benefits of Premarin and Provera?
Wyeth has a big presence in hormone replacement therapy, selling drugs women use to treat the symptoms of menopause. Sales of Wyeth's hormone replacement drugs, Premarin and Prempro, reached nearly $2 billion in 2001. The field took a big hit in 2002, when a large federal study found that women who took certain hormones had a higher risk of breast cancer, heart disease and stroke.